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Review Article| Volume 49, ISSUE 2, P461-474, June 2022

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Long-Term Impact of Early Nutritional Management

      Growth patterns which follow growth measures over time are the strongest indicators of neurodevelopmental outcomes in preterm infants.

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      References

        • Clouchoux C.
        • Guizard N.
        • Evans A.C.
        • et al.
        Normative fetal brain growth by quantitative in vivo magnetic resonance imaging.
        Am J Obstet Gynecol. 2012; 206: 173.e1-8
        • Cormack B.E.
        • Harding J.E.
        • Miller S.P.
        • et al.
        The influence of early nutrition on brain growth and neurodevelopment in extremely preterm babies: a narrative review.
        Nutrients. 2019; 11: 2029
        • Volpe J.J.
        Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances.
        Lancet Neurol. 2009; 8: 110-124
        • Dubois J.
        • Benders M.
        • Cachia A.
        • et al.
        Mapping the early cortical folding process in the preterm newborn brain.
        Cereb Cortex. 2008; 18: 1444-1454
        • Lubsen J.
        • Vohr B.
        • Myers E.
        • et al.
        Microstructural and functional connectivity in the developing preterm brain.
        Semin Perinatol. 2011; 35: 34-43
        • Pascal A.
        • Govaert P.
        • Oostra A.
        • et al.
        Neurodevelopmental outcome in very preterm and very-low-birthweight infants born over the past decade: a meta-analytic review.
        Dev Med Child Neurol. 2018; 60: 342-355
        • Adams-Chapman I.
        • Heyne R.J.
        • DeMauro S.B.
        • et al.
        Neurodevelopmental impairment among extremely preterm infants in the neonatal research network.
        Pediatrics. 2018; 141
        • Allotey J.
        • Zamora J.
        • Cheong-See F.
        • et al.
        Cognitive, motor, behavioural and academic performances of children born preterm: a meta-analysis and systematic review involving 64 061 children.
        BJOG. 2018; 125: 16-25
        • McGowan E.C.
        • Vohr B.R.
        Neurodevelopmental follow-up of preterm infants: what is new?.
        Pediatr Clin North Am. 2019; 66: 509-523
        • Back S.A.
        • Miller S.P.
        Brain injury in premature neonates: a primary cerebral dysmaturation disorder?.
        Ann Neurol. 2014; 75: 469-486
        • Hsiao C.C.
        • Tsai M.L.
        • Chen C.C.
        • et al.
        Early optimal nutrition improves neurodevelopmental outcomes for very preterm infants.
        Nutr Rev. 2014; 72: 532-540
        • Fenton T.R.
        • Kim J.H.
        A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants.
        Bmc Pediatr. 2013; 13
        • Villar J.
        • Giuliani F.
        • Bhutta Z.A.
        • et al.
        Postnatal growth standards for preterm infants: the preterm postnatal follow-up study of the INTERGROWTH-21(st) project.
        Lancet Glob Health. 2015; 3: e681-e691
        • Olsen I.E.
        • Groveman S.A.
        • Lawson M.L.
        • et al.
        New intrauterine growth curves based on United States data.
        Pediatrics. 2010; 125: e214-e224
        • Ehrenkranz R.A.
        • Younes N.
        • Lemons J.A.
        • et al.
        Longitudinal growth of hospitalized very low birth weight infants.
        Pediatrics. 1999; 104: 280-289
        • Zozaya C.
        • Diaz C.
        • Saenz de Pipaon M.
        How should we define postnatal growth restriction in preterm infants?.
        Neonatology. 2018; 114: 177-180
        • Shah P.S.
        • Wong K.Y.
        • Merko S.
        • et al.
        Postnatal growth failure in preterm infants: ascertainment and relation to long-term outcome.
        J Perinat Med. 2006; 34: 484-489
        • Pfister K.M.
        • Ramel S.E.
        Linear growth and neurodevelopmental outcomes.
        Clin Perinatol. 2014; 41: 309-321
        • Pfister K.M.
        • Zhang L.
        • Miller N.C.
        • et al.
        Early body composition changes are associated with neurodevelopmental and metabolic outcomes at 4 years of age in very preterm infants.
        Pediatr Res. 2018; 84: 713-718
        • Ehrenkranz R.A.
        • Dusick A.M.
        • Vohr B.R.
        • et al.
        Growth in the neonatal intensive care unit influences neurodevelopmental and growth outcomes of extremely low birth weight infants.
        Pediatrics. 2006; 117: 1253-1261
        • Belfort M.B.
        • Rifas-Shiman S.L.
        • Sullivan T.
        • et al.
        Infant growth before and after term: effects on neurodevelopment in preterm infants.
        Pediatrics. 2011; 128: e899-e906
        • Franz A.R.
        • Pohlandt F.
        • Bode H.
        • et al.
        Intrauterine, early neonatal, and postdischarge growth and neurodevelopmental outcome at 5.4 years in extremely preterm infants after intensive neonatal nutritional support.
        Pediatrics. 2009; 123: e101-e109
        • Fenton T.R.
        • Anderson D.
        • Groh-Wargo S.
        • et al.
        An attempt to standardize the calculation of growth velocity of preterm infants-evaluation of practical bedside methods.
        J Pediatr. 2018; 196: 77-83
        • Sicard M.
        • Nusinovici S.
        • Hanf M.
        • et al.
        Fetal and postnatal head circumference growth: synergetic factors for neurodevelopmental outcome at 2 years of age for preterm infants.
        Neonatology. 2017; 112: 122-129
        • Raghuram K.
        • Yang J.
        • Church P.T.
        • et al.
        Head growth trajectory and neurodevelopmental outcomes in preterm neonates.
        Pediatrics. 2017; 140: e20170216
        • Villar J.
        • Gunier R.B.
        • Tshivuila-Matala C.O.O.
        • et al.
        Fetal cranial growth trajectories are associated with growth and neurodevelopment at 2 years of age: INTERBIO-21st Fetal Study.
        Nat Med. 2021; 27: 647-652
        • Ramel S.E.
        • Demerath E.W.
        • Gray H.L.
        • et al.
        The relationship of poor linear growth velocity with neonatal illness and two-year neurodevelopment in preterm infants.
        Neonatology. 2012; 102: 19-24
        • Simon L.
        • Theveniaut C.
        • Flamant C.
        • et al.
        In preterm infants, length growth below expected growth during hospital stay predicts poor neurodevelopment at 2 years.
        Neonatology. 2018; 114: 135-141
        • Bell K.A.
        • Matthews L.G.
        • Cherkerzian S.
        • et al.
        Associations of growth and body composition with brain size in preterm infants.
        J Pediatr. 2019; 214: 20-26.e22
        • Olsen I.E.
        • Lawson M.L.
        • Ferguson A.N.
        • et al.
        BMI curves for preterm infants.
        Pediatrics. 2015; 135: e572-e581
        • Meyers J.M.
        • Tan S.
        • Bell E.F.
        • et al.
        Neurodevelopmental outcomes among extremely premature infants with linear growth restriction.
        J Perinatol. 2019; 39: 193-202
        • Paviotti G.
        • De Cunto A.
        • Zennaro F.
        • et al.
        Higher growth, fat and fat-free masses correlate with larger cerebellar volumes in preterm infants at term.
        Acta Paediatr. 2017; 106: 918-925
        • Ramel S.E.
        • Gray H.L.
        • Christiansen E.
        • et al.
        Greater early gains in fat-free mass, but not fat mass, are associated with improved neurodevelopment at 1 year corrected age for prematurity in very low birth weight preterm infants.
        J Pediatr. 2016; 173: 108-115
        • Rochow N.
        • Landau-Crangle E.
        • So H.Y.
        • et al.
        Z-score differences based on cross-sectional growth charts do not reflect the growth rate of very low birth weight infants.
        PLoS One. 2019; 14: e0216048
        • Goldberg D.L.
        • Becker P.J.
        • Brigham K.
        • et al.
        Identifying malnutrition in preterm and neonatal populations: recommended indicators.
        J Acad Nutr Diet. 2018; 118: 1571-1582
        • Fenton T.R.
        • Griffin I.J.
        • Groh-Wargo S.
        • et al.
        Very low birthweight preterm infants: a 2020 evidence analysis center evidence-based nutrition practice guideline.
        J Acad Nutr Diet. 2021; 122: 182-206
        • Osborn D.A.
        • Schindler T.
        • Jones L.J.
        • et al.
        Higher versus lower amino acid intake in parenteral nutrition for newborn infants.
        Cochrane Database Syst Rev. 2018; 3: CD005949
        • Buddhavarapu S.
        • Manickaraj S.
        • Lodha A.
        • et al.
        Does high protein intake during first week of life improve growth and neurodevelopmental outcome at 18 months corrected age in extremely preterm infants?.
        Indian J Pediatr. 2016; 83: 915-921
        • Cester E.A.
        • Bloomfield F.H.
        • Taylor J.
        • et al.
        Do recommended protein intakes improve neurodevelopment in extremely preterm babies?.
        Arch Dis Child Fetal Neonatal Ed. 2015; 100: F243-F247
        • Blanco C.L.
        • Gong A.K.
        • Schoolfield J.
        • et al.
        Impact of early and high amino acid supplementation on ELBW infants at 2 years.
        J Pediatr Gastroenterol Nutr. 2012; 54: 601-607
        • Bellagamba M.P.
        • Carmenati E.
        • D'Ascenzo R.
        • et al.
        One extra gram of protein to preterm infants from birth to 1800 g: a single-blinded randomized clinical trial.
        J Pediatr Gastroenterol Nutr. 2016; 62: 879-884
        • Stephens B.E.
        • Walden R.V.
        • Gargus R.A.
        • et al.
        First-week protein and energy intakes are associated with 18-month developmental outcomes in extremely low birth weight infants.
        Pediatrics. 2009; 123: 1337-1343
        • Balakrishnan M.
        • Jennings A.
        • Przystac L.
        • et al.
        Growth and neurodevelopmental outcomes of early, high-dose parenteral amino acid intake in very low birth weight infants: a randomized controlled trial.
        JPEN J Parenter Enteral Nutr. 2018; 42: 597-606
        • Bloomfield F.H.
        • Crowther C.A.
        • Harding J.E.
        • et al.
        The ProVIDe study: the impact of protein intravenous nutrition on development in extremely low birthweight babies.
        BMC Pediatr. 2015; 15: 100
        • Cormack B.E.
        • Jiang Y.
        • Harding J.E.
        • et al.
        Relationships between neonatal nutrition and growth to 36 weeks' corrected age in ELBW babies-secondary cohort analysis from the provide trial.
        Nutrients. 2020; 12: 760
        • Morgan C.
        • McGowan P.
        • Herwitker S.
        • et al.
        Postnatal head growth in preterm infants: a randomized controlled parenteral nutrition study.
        Pediatrics. 2014; 133: e120-e128
        • Shim S.Y.
        • Ahn H.M.
        • Cho S.J.
        • et al.
        Early aggressive nutrition enhances language development in very low-birthweight infants.
        Pediatr Int. 2014; 56: 845-850
        • dit Trolli S.E.
        • Kermorvant-Duchemin E.
        • Huon C.
        • et al.
        Early lipid supply and neurological development at one year in very low birth weight (VLBW) preterm infants.
        Early Hum Dev. 2012; 88: S25-S29
        • Makrides M.
        • Gibson R.A.
        • McPhee A.J.
        • et al.
        Neurodevelopmental outcomes of preterm infants fed high-dose docosahexaenoic acid: a randomized controlled trial.
        JAMA. 2009; 301: 175-182
        • Collins C.T.
        • Gibson R.A.
        • Anderson P.J.
        • et al.
        Neurodevelopmental outcomes at 7 years' corrected age in preterm infants who were fed high-dose docosahexaenoic acid to term equivalent: a follow-up of a randomised controlled trial.
        BMJ Open. 2015; 5: e007314
        • Moon K.
        • Rao S.C.
        • Schulzke S.M.
        • et al.
        Long-chain polyunsaturated fatty acid supplementation in preterm infants.
        Cochrane Database Syst Rev. 2016; 12: CD000375
        • Carlson S.E.
        • Werkman S.H.
        • Tolley E.A.
        Effect of long-chain n-3 fatty acid supplementation on visual acuity and growth of preterm infants with and without bronchopulmonary dysplasia.
        Am J Clin Nutr. 1996; 63: 687-697
        • Henriksen C.
        • Haugholt K.
        • Lindgren M.
        • et al.
        Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid.
        Pediatrics. 2008; 121: 1137-1145
        • Westerberg A.C.
        • Schei R.
        • Henriksen C.
        • et al.
        Attention among very low birth weight infants following early supplementation with docosahexaenoic and arachidonic acid.
        Acta Paediatr. 2011; 100: 47-52
        • Bhatia J.
        Human milk and the premature infant.
        Ann Nutr Metab. 2013; 62: 8-14
        • Pei J.J.
        • Tang J.
        [A review on the relationship between breast milk nutrients and brain development in preterm infants].
        Zhongguo Dang Dai Er Ke Za Zhi. 2019; 21: 607-612
        • Lechner B.E.
        • Vohr B.R.
        Neurodevelopmental outcomes of preterm infants fed human milk: a systematic review.
        Clin Perinatol. 2017; 44: 69-83
        • Vohr B.R.
        • Poindexter B.B.
        • Dusick A.M.
        • et al.
        Persistent beneficial effects of breast milk ingested in the neonatal intensive care unit on outcomes of extremely low birth weight infants at 30 months of age.
        Pediatrics. 2007; 120: e953-e959
        • Vohr B.R.
        • Poindexter B.B.
        • Dusick A.M.
        • et al.
        Beneficial effects of breast milk in the neonatal intensive care unit on the developmental outcome of extremely low birth weight infants at 18 months of age.
        Pediatrics. 2006; 118: e115-e123
        • Belfort M.B.
        Human milk and preterm infant brain development.
        Breastfeed Med. 2018; 13: S23-S25
        • Belfort M.B.
        • Anderson P.J.
        • Nowak V.A.
        • et al.
        Breast milk feeding, brain development, and neurocognitive outcomes: a 7-year longitudinal study in infants born at less than 30 weeks' gestation.
        J Pediatr. 2016; 177: 133-139.e131
        • Committee On N, Section On B, Committee On F, Committee On N, Section On B, Committee On F, Newborn
        Donor human milk for the high-risk infant: preparation, safety, and usage options in the United States.
        Pediatrics. 2017; 139: e20163440
        • Hård A.L.
        • Nilsson A.K.
        • Lund A.M.
        • et al.
        Review shows that donor milk does not promote the growth and development of preterm infants as well as maternal milk.
        Acta Paediatr. 2019; 108: 998-1007
        • Quigley M.
        • Embleton N.D.
        • McGuire W.
        Formula versus donor breast milk for feeding preterm or low birth weight infants.
        Cochrane Database Syst Rev. 2018; 6: Cd002971
        • Bhatia J.
        Human milk for preterm infants and fortification.
        Nestle Nutr Inst Workshop Ser. 2016; 86: 109-119
        • Mangili G.
        • Garzoli E.
        Feeding of preterm infants and fortification of breast milk.
        Pediatr Med Chir. 2017; 39: 158
        • Radmacher P.G.
        • Adamkin D.H.
        Fortification of human milk for preterm infants.
        Semin Fetal Neonatal Med. 2017; 22: 30-35
        • Gao C.
        • Miller J.
        • Collins C.T.
        • et al.
        Comparison of different protein concentrations of human milk fortifier for promoting growth and neurological development in preterm infants.
        Cochrane Database Syst Rev. 2020; 11: Cd007090
        • Premkumar M.H.
        • Pammi M.
        • Suresh G.
        Human milk-derived fortifier versus bovine milk-derived fortifier for prevention of mortality and morbidity in preterm neonates.
        Cochrane Database Syst Rev. 2019; 2019: CD013145
        • Alyahya W.
        • Simpson J.
        • Garcia A.L.
        • et al.
        Early versus delayed fortification of human milk in preterm infants: a systematic review.
        Neonatology. 2020; 117: 24-32
        • Brownell E.A.
        • Matson A.P.
        • Smith K.C.
        • et al.
        Dose-response relationship between donor human milk, mother's own milk, preterm formula, and neonatal growth outcomes.
        J Pediatr Gastroenterol Nutr. 2018; 67: 90-96
        • Lin Y.H.
        • Hsu Y.C.
        • Lin M.C.
        • et al.
        The association of macronutrients in human milk with the growth of preterm infants.
        PLoS One. 2020; 15: e0230800
        • Nzegwu N.I.
        • Ehrenkranz R.A.
        Post-discharge nutrition and the VLBW infant: to supplement or not supplement? A review of the current evidence.
        Clin Perinatol. 2014; 41: 463-474
        • O'Connor D.L.
        • Unger S.
        Post-discharge nutrition of the breastfed preterm infant.
        Semin Fetal Neonatal Med. 2013; 18: 124-128
        • Teller I.C.
        • Embleton N.D.
        • Griffin I.J.
        • et al.
        Post-discharge formula feeding in preterm infants: a systematic review mapping evidence about the role of macronutrient enrichment.
        Clin Nutr. 2016; 35: 791-801
        • Young L.
        • Embleton N.D.
        • McGuire W.
        Nutrient-enriched formula versus standard formula for preterm infants following hospital discharge.
        Cochrane Database Syst Rev. 2016; 12: CD004696
        • Parker M.G.
        • Greenberg L.T.
        • Edwards E.M.
        • et al.
        National trends in the provision of human milk at hospital discharge among very low-birth-weight infants.
        JAMA Pediatr. 2019; 173: 961-968
        • Lapillonne A.
        • O'Connor D.L.
        • Wang D.
        • et al.
        Nutritional recommendations for the late-preterm infant and the preterm infant after hospital discharge.
        J Pediatr. 2013; 162: S90-S100
        • Fernandes A.I.
        • Gollins L.A.
        • Hagan J.L.
        • et al.
        Very preterm infants who receive transitional formulas as a complement to human milk can achieve catch-up growth.
        J Perinatol. 2019; 39: 1492-1497
        • Belfort M.B.
        • Gillman M.W.
        • Buka S.L.
        • et al.
        Preterm infant linear growth and adiposity gain: trade-offs for later weight status and intelligence quotient.
        J Pediatr. 2013; 163: 1564-1569.e1562
        • Scheurer J.M.
        • Zhang L.
        • Plummer E.A.
        • et al.
        Body composition changes from infancy to 4 years and associations with early childhood cognition in preterm and full-term children.
        Neonatology. 2018; 114: 169-176
        • Singhal A.
        • Fewtrell M.
        • Cole T.J.
        • et al.
        Low nutrient intake and early growth for later insulin resistance in adolescents born preterm.
        Lancet. 2003; 361: 1089-1097
        • Kerkhof G.F.
        • Willemsen R.H.
        • Leunissen R.W.
        • et al.
        Health profile of young adults born preterm: negative effects of rapid weight gain in early life.
        J Clin Endocrinol Metab. 2012; 97: 4498-4506
        • Vohr B.R.
        • Allan W.
        • Katz K.H.
        • et al.
        Early predictors of hypertension in prematurely born adolescents.
        Acta Paediatr. 2010; 99: 1812-1818
        • Vohr B.R.
        • Heyne R.
        • Bann C.M.
        • et al.
        Extreme preterm infant rates of overweight and obesity at school age in the SUPPORT neuroimaging and neurodevelopmental outcomes cohort.
        J Pediatr. 2018; 200: 132-139.e133
        • Vohr B.R.
        • Heyne R.
        • Bann C.
        • et al.
        High blood pressure at early school age among extreme preterms.
        Pediatrics. 2018; 142: e20180269
        • Lowe Jr., W.L.
        • Scholtens D.M.
        • Kuang A.
        • et al.
        Hyperglycemia and Adverse Pregnancy Outcome Follow-up Study (HAPO FUS): maternal gestational diabetes mellitus and childhood glucose metabolism.
        Diabetes Care. 2019; 42: 372-380
        • Gademan M.G.
        • Vermeulen M.
        • Oostvogels A.J.
        • et al.
        Maternal prepregnancy BMI and lipid profile during early pregnancy are independently associated with offspring's body composition at age 5-6 years: the ABCD study.
        PLoS One. 2014; 9: e94594
        • Ouyang F.
        • Parker M.G.
        • Luo Z.C.
        • et al.
        Maternal BMI, gestational diabetes, and weight gain in relation to childhood obesity: the mediation effect of placental weight.
        Obesity (Silver Spring). 2016; 24: 938-946
        • Johnson M.J.
        • Wootton S.A.
        • Leaf A.A.
        • et al.
        Preterm birth and body composition at term equivalent age: a systematic review and meta-analysis.
        Pediatrics. 2012; 130: E640-E649
        • Balakrishnan M.
        • Jennings A.
        • Przystac L.
        • et al.
        Growth and Neurodevelopmental Outcomes of Early, High-Dose Parenteral Amino Acid Intake in Very Low Birth Weight Infants: A Randomized Controlled Trial.
        JPEN J Parenter Enteral Nutr. 2018; 42: 597-606
        • Burattini I.
        • Bellagamba M.P.
        • Spagnoli C.
        • et al.
        Targeting 2.5 versus 4 g/kg/day of amino acids for extremely low birth weight infants: a randomized clinical trial.
        J Pediatr. 2013; 163 (e1271): 1278-1282
        • Power V.A.
        • Spittle A.J.
        • Lee K.J.
        • et al.
        Nutrition, Growth, Brain Volume, and Neurodevelopment in Very Preterm Children.
        J Pediatr. 2019; 215: 50-55.e3
        • Cester E.A.
        • Bloomfield F.H.
        • Taylor J.
        • et al.
        Do recommended protein intakes improve neurodevelopment in extremely preterm babies?.
        Arch Dis Child Fetal Neonatal Ed. 2015; 100: F243-F247
        • Furman L.
        • Minich N.
        Efficiency of breastfeeding as compared to bottle-feeding in very low birth weight (VLBW, <1.5 kg) infants.
        J Perinatol. 2004; 24: 706-713
        • Pinelli J.
        • Saigal S.
        • Atkinson S.A.
        Effect of breastmilk consumption on neurodevelopmental outcomes at 6 and 12 months of age in VLBW infants.
        Adv Neonatal Care. 2003; 3: 76-87
        • Tanaka K.
        • Kon N.
        • Ohkawa N.
        • et al.
        Does breastfeeding in the neonatal period influence the cognitive function of very-low-birth-weight infants at 5 years of age?.
        Brain Dev. 2009; 31: 288-293
        • Horwood L.J.
        • Darlow B.A.
        • Mogridge N.
        Breast milk feeding and cognitive ability at 7-8 years.
        Arch Dis Child Fetal Neonatal Ed. 2001; 84: F23-F27
        • Johnson S.
        • Wolke D.
        • Hennessy E.
        • et al.
        Educational outcomes in extremely preterm children: neuropsychological correlates and predictors of attainment.
        Dev Neuropsychol. 2011; 36: 74-95
        • Isaacs E.B.
        • Fischl B.R.
        • Quinn B.T.
        • et al.
        Impact of breast milk on intelligence quotient, brain size, and white matter development.
        Pediatr Res. 2010; 67: 357-362
        • Beaino G.
        • Khoshnood B.
        • Kaminski M.
        • et al.
        Predictors of the risk of cognitive deficiency in very preterm infants: the EPIPAGE prospective cohort.
        Acta Paediatr. 2011; 100: 370-378
        • Roze J.C.
        • Darmaun D.
        • Boquien C.Y.
        • et al.
        The apparent breastfeeding paradox in very preterm infants: relationship between breast feeding, early weight gain and neurodevelopment based on results from two cohorts, EPIPAGE and LIFT.
        BMJ Open. 2012; 2: e000834
        • Brown J.V.
        • Embleton N.D.
        • Harding J.E.
        • et al.
        Multi-nutrient fortification of human milk for preterm infants.
        Cochrane Database Syst Rev. 2016; : CD000343