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Research Article| Volume 22, ISSUE 1, P177-193, March 1995

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Metabolic Balance Studies in Premature Infants

  • Judith A. Ernst
    Correspondence
    Address reprint requests to: Judith A. Ernst, DMSc, RD, CS, James Whitcomb Riley Hospital for Children, 702 Barnhill Drive, Department of Nutrition and Dietetics, Room 1010, Indianapolis, IN 46202-5200
    Affiliations
    From the Department of Nutrition and Dietetics Indiana University School of Medicine, Indianapolis, Indiana

    James Whitcomb Riley Hospital for Children, Indianapolis, Indiana
    Search for articles by this author
  • Wendy K. Cruse
    Affiliations
    James Whitcomb Riley Hospital for Children, Indianapolis, Indiana
    Search for articles by this author
  • James A. Lemons
    Affiliations
    From the Department of Section of Neonatal / Perinatal Medicine, Indiana University School of Medicine, Indianapolis, Indiana

    James Whitcomb Riley Hospital for Children, Indianapolis, Indiana
    Search for articles by this author
DOI:https://doi.org/10.1016/S0095-5108(18)30307-5
Metabolic Balance Studies in Premature Infants
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      Over the past decades metabolic balance studies have been extensively used for the purpose of determining the retention rates of nutrients ingested by neonates. Traditionally, data derived from these studies have been used to estimate nutritional requirements in both full-term and premature infants. This article provides a historical review of the methodology used in classic metabolic balance studies performed in neonates since 1955. In addition, descriptions of new methodologies that improve the reliability and reproducibility of metabolic balance studies conducted in premature infants that include: (1) the recognition that an acclimation period of steady and sufficient energy intake is necessary prior to the initiation of the balance study; (2) the use of a minimum period of 72 hours for the total duration of balance study; and (3) the use of stool markers to time the period. Also described in this article are the retention rates of calcium and fat that were measured in premature infants by means of metabolic balance studies conducted with the use of recommended methodology.
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      Article info

      Footnotes

      This work was supported, in part, by Ross Laboratories, Columbus, OH

      Identification

      DOI: https://doi.org/10.1016/S0095-5108(18)30307-5

      Copyright

      © 1995 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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