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Insulin resistance syndrome is a cluster of physiologic abnormalities including hyperinsulinemia
and glucose intolerance, dyslipidemia, and hypertension. Patients with this cluster
of physiologic disturbances are at increased risk for stroke, renal failure, and heart
disease. Insulin resistance is the causal mechanism of gestational diabetes and may
be involved in the pathogenesis of preeclampsia. Implications of diagnosing a population
that may be at future risk for stroke and heart disease are discussed, along with
therapeutic strategies that may decrease long-term complications in this group.
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© 1998 Elsevier Inc. Published by Elsevier Inc. All rights reserved.